{"id":1293,"date":"2023-01-18T14:00:00","date_gmt":"2023-01-18T13:00:00","guid":{"rendered":"https:\/\/endoyellow.com\/?p=1293"},"modified":"2023-01-18T14:27:00","modified_gmt":"2023-01-18T13:27:00","slug":"histoire-endometriose","status":"publish","type":"post","link":"https:\/\/endoyellow.com\/index.php\/2023\/01\/18\/histoire-endometriose\/","title":{"rendered":"Histoire de l’endom\u00e9triose"},"content":{"rendered":"\t\t
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L\u2019endom\u00e9triose, on en parle de plus en plus et c\u2019est une tr\u00e8s bonne chose ! Pour autant, on parle peu de QUI a d\u00e9couvert l\u2019endom\u00e9triose. Et surtout QUAND ? On a le sentiment que c’est une maladie nouvelle, mais est-ce vraiment le cas ?<\/strong><\/p>

\ud83e\uddd0Et si tu partais \u00e0 la d\u00e9couverte de l\u2019histoire de l\u2019endom\u00e9triose ?\u00a0<\/span>
<\/strong><\/p>

Egypte, Antiquit\u00e9 et Moyen-\u00c2ge : sympt\u00f4mes, infertilit\u00e9, hyst\u00e9rie<\/h3>

L\u2019endom\u00e9triose existait d\u00e9j\u00e0 \u00e0 l’\u00e9poque des Egyptiens il y a 4000 ans. Le papyrus Ebers (en 1550 avant JC) consid\u00e9r\u00e9 comme l\u2019un des plus anciens textes m\u00e9dicaux \u00e9voque des \u201ctroubles douloureux des menstruations\u201d.<\/p>

Il y a 500 ans, durant l\u2019Antiquit\u00e9, des sympt\u00f4mes similaires \u00e0 l\u2019endom\u00e9triose sont \u00e9galement d\u00e9crits, notamment dans le corpus hippocratique,<\/em> Platon et d\u2019autres auteurs gr\u00e9co-romains. On y parle de violentes contractions ut\u00e9rines, d’inflammation, d’\u00e9tat syncopal ou convulsif. On reconnait un dysfonctionnement menstruel qui entra\u00eene des douleurs ut\u00e9rines, voire une infertilit\u00e9, et on identifie la grossesse comme un rem\u00e8de.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\u00c0 l’\u00e9poque, on parle d\u2019hyst\u00e9rie<\/em>, en r\u00e9f\u00e9rence au mot grec hustera<\/em>, \u201cla matrice\u201d, qui veut dire l’\u201dut\u00e9rus\u201d. Malheureusement, ces douleurs ut\u00e9rines sont souvent associ\u00e9es \u00e0 un ut\u00e9rus \u00ab\u2009vagabond\u2009\u00bb priv\u00e9 de sa fonction reproductive \u00e0 l’Antiquit\u00e9, ou aux p\u00e9ch\u00e9s et possession d\u00e9moniaque au Moyen \u00c2ge. Donc trahissant plus un comportement d\u00e9viant qu’une r\u00e9elle pathologie\u2026 Ces croyances vont \u00e9videmment freiner la prise en compte de l\u2019endom\u00e9triose au fil de l’histoire. En guise de traitement, les femmes se voient alors attach\u00e9es la t\u00eate en bas \u00e0 une \u00e9chelle et secou\u00e9es pour \u201cremettre leur ut\u00e9rus en place\u201d, et plus tard, exorcis\u00e9es, exil\u00e9es ou carr\u00e9ment ex\u00e9cut\u00e9es.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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17s et 18e si\u00e8cles : l\u00e9sions, douleurs et inflammations<\/h3>

En 1690, le m\u00e9decin allemand Daniel Shroen<\/strong> d\u00e9crit \u00ab\u00a0des ulc\u00e8res qui ont tendance \u00e0 former des l\u00e9sions\u00a0\u00bb. Ces l\u00e9sions qu\u2019il consid\u00e9rait comme \u00ab\u00a0troubles f\u00e9minins caract\u00e9ristiques de celles qui sont en pleine maturation sexuelle\u00a0\u00bb non seulement s’\u00e9tendaient en taille, mais \u00e9taient aussi susceptibles de provoquer des h\u00e9morragies.<\/p>

En 1776, le m\u00e9decin \u00e9cossais Louis Brotherson<\/strong> \u00e9voque la douleur ressentie par les femmes \u00e0 cause de cette maladie qui les affecte de mani\u00e8re n\u00e9gative et les contraint \u00e0 vivre dans la crainte de leurs sympt\u00f4mes.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Au 18e si\u00e8cle, le m\u00e9decin \u00e9cossais William Broughton et le m\u00e9decin anglais Robert Tailford<\/strong> d\u00e9crivent, avec l\u2019essor de l’examen post-mortem des l\u00e9sions endom\u00e9triales, des structures qui prolif\u00e8rent et ressemblent \u00e0 des polypes. D’autres m\u00e9decins observent \u00e9galement un mod\u00e8le de propagation de l’inflammation autour du vagin.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\u00c0 cette \u00e9poque, \u201cl’hyst\u00e9rie\u201d est alors parfois diagnostiqu\u00e9e comme une nymphomanie. C\u2019est la \u201cfolie ut\u00e9rine\u201d ou furor uterinus<\/em>. Marie-Antoinette et Pauline Bonaparte en ont fait les frais en leur temps parce qu\u2019elles pr\u00e9sentent alors troubles gyn\u00e9cologiques et douleurs pelviennes.<\/p>

19e si\u00e8cle : 1\u00e8re description de l’endom\u00e9triose<\/h3>

En 1860, Karel Rokitansky est le premier \u00e0 d\u00e9crire l’endom\u00e9triose,<\/strong> comme la \u00ab\u00a0pr\u00e9sence de muqueuse ut\u00e9rine en dehors de l’ut\u00e9rus\u00a0\u00bb. Il d\u00e9couvre \u00e0 l’occasion d’une autopsie une grosseur ut\u00e9rine anormale. En examinant ce polype au microscope, il d\u00e9couvre qu’il est constitu\u00e9 par des cellules similaires \u00e0 celles de l’endom\u00e8tre.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Pour autant, ce n’est pas lui qui lui donne son nom d\u2019endom\u00e9triose puisqu\u2019il l’appelle alors cystosarcoma<\/em>. En revanche, Rokitansky est aussi le premier \u00e0 d\u00e9crire une forme d’ad\u00e9nomyose<\/a>.<\/p>

En 1899, Russel WW<\/strong>\u00a0d\u00e9crit l’endom\u00e9triome ovarien comme un ‘\u00a0\u00bbovaire contenant une muqueuse ut\u00e9rine\u00a0\u00bb, un \u00ab\u00a0h\u00e9matomes de l’ovaire\u00a0\u00bb ou un \u00ab\u00a0kyste chocolat\u00a0\u00bb.<\/p>

Les techniques utilis\u00e9es \u00e0 la fin du XIXe si\u00e8cle pour traiter l\u2019endom\u00e9triose comprenaient, entre autres, les interventions non chirurgicales, l’\u00e9lectrocaut\u00e9risation, la dilatation et le curetage, les excisions partielles, l’ovariectomie et l’hyst\u00e9rectomie.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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L\u2019\u201dhyst\u00e9rie\u201d reste bien pr\u00e9sente \u00e0 cette \u00e9poque avec Syndenham et Charcot, deux sp\u00e9cialistes du sujet qui d\u00e9fendent l\u2019hypoth\u00e8se psychologique.<\/p>

D\u00e9but du 20e si\u00e8cle : un nom, une th\u00e9orie, des avanc\u00e9es technologiques<\/h3>

En 1920, le chirurgien canadien Thomas Stephen Cullen<\/strong> d\u00e9crit l’endom\u00e9triose sous le nom d'\u00a0\u00bbad\u00e9nomyome\u00a0\u00bb et pr\u00e9cise la maladie : type de pathologie, diagnostic et traitement de l\u2019endom\u00e9triose profonde. Il \u00e9tablit que l’endom\u00e9triose ovarienne et profonde constituaient une seule et m\u00eame maladie caract\u00e9ris\u00e9e par la pr\u00e9sence de \u00ab\u00a0tissu ad\u00e9nomyomateux\u00a0\u00bb en dehors de la cavit\u00e9 ut\u00e9rine. Les d\u00e9couvertes pionni\u00e8res de Cullen comprennent la premi\u00e8re description des l\u00e9sions r\u00e9nales dues \u00e0 l’endom\u00e9triose et la reconnaissance du fait que l’hyst\u00e9rectomie ne gu\u00e9rit pas n\u00e9cessairement la maladie.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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En 1922, le Dr John Sampson<\/strong> observe que les l\u00e9sion sont h\u00e9morragiques au moment des menstruation et expose sa th\u00e9orie du \u201creflux<\/em> de sang menstruel<\/em>\u2009\u00bb, qui s\u2019\u00e9chappe par les trompes de Fallope et s\u2019infiltre dans l\u2019abdomen. C\u2019est encore souvent la th\u00e9orie la plus retenue dans l\u2019explication de l\u2019apparition de la maladie, bien que de multiples causes sont aujourd\u2019hui \u00e9voqu\u00e9es ou font l\u2019objet de recherches. En effet, 10% des femmes d\u00e9veloppent la maladie alors que 90% des femmes ont des r\u00e8gles r\u00e9trogrades, c\u2019est-\u00e0-dire qui s\u2019\u00e9coulent \u00e9galement vers l\u2019int\u00e9rieur du ventre.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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En 1927, l’article de Sampson intitul\u00e9 \u00ab\u00a0Peritoneal endometriosis due to menstrual dissemination of endometrial tissue into the peritoneal cavity\u00a0\u00bb est le premier \u00e0 utiliser officiellement le terme \u00ab\u00a0endom\u00e9triose\u00a0\u00bb.<\/strong><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Dans les ann\u00e9es 1930 et 1940,<\/strong> on d\u00e9crit l’endom\u00e9triose dans les poumons, les intestins, le c\u00f4lon, le rectum, la vessie, les ganglions lymphatiques, le col de l’ut\u00e9rus et d’autres endroits. Notamment gr\u00e2ce \u00e0 de nouvelles techniques d’endoscopie pelvienne qui permettent une r\u00e9volution dans la prise en charge de l’endom\u00e9triose en diff\u00e9renciant les causes de saignement intra-abdominal et d’appendicite par exemple. C\u2019est aussi en 1940 que d\u00e9bute le traitement hormonal avec successivement des androg\u00e8nes, \u0153strog\u00e8nes, \u0153stroprogestatifs, agents antigonadotropes et antiprogestatifs.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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En parall\u00e8le, les m\u00e9decins incitent les femmes \u00e0 avoir des enfants plus t\u00f4t pour contrer l’impact potentiel de l’endom\u00e9triose sur la fertilit\u00e9. D\u2019ailleurs, l’endom\u00e9triose a souvent \u00e9t\u00e9 diagnostiqu\u00e9e \u00e0 tort comme une maladie inflammatoire sexuellement transmissible ! Enfin, les clich\u00e9s ont la vie dure et les douleurs pelviennes sont encore li\u00e9es \u00e0 la maladie mentale.<\/p>

Fin du XXe et XXIe si\u00e8cle : chirurgie, g\u00e9n\u00e9tique et politique<\/h3>

Entre les ann\u00e9es 50 et la fin des ann\u00e9es 70<\/strong>, les techniques chirurgicales connaissent de grandes avanc\u00e9es. La laparoscopie (ou c\u0153lioscopie qui permet par une petite ouverture de la paroi de l’abdomen d’observer et d’intervenir sur les organes) fait timidement son entr\u00e9e en compl\u00e9ment des chirurgies abdominales ouvertes (laparotomies) et hyst\u00e9rectomies qui sont encore largement pratiqu\u00e9es.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Dans les ann\u00e9es 80 et 90,<\/strong> les progr\u00e8s dans la connaissance et le traitement de l’endom\u00e9triose se poursuivent : laparoscopie \u00e0 orifice unique, biomarqueur potentiel de l’endom\u00e9triose, endom\u00e9triose infiltrante profonde (DIE), dysfonctionnement immunitaire dans l’endom\u00e9triose, etc.<\/p>

Dans les ann\u00e9es 2000,<\/strong> la g\u00e9n\u00e9tique entre en jeu. En 2004, le Dr Linda C. Giudice contribue \u00e0 la compr\u00e9hension g\u00e9n\u00e9tique et mol\u00e9culaire de l’endom\u00e9triose et en 2012, le Dr Hugh S. Taylor et ses coll\u00e8gues d\u00e9couvrent une mutation du g\u00e8ne KRAS en association avec l’endom\u00e9triose.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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Ces derni\u00e8res ann\u00e9es,<\/strong> on constate des avanc\u00e9es plus \u201cpolitiques\u201d avec en septembre 2020 l\u2019enseignement de l\u2019endom\u00e9triose dans les cours de second cycle des \u00e9tudes de m\u00e9decine. L’ann\u00e9e 2022 marque le lancement d’un\u00a0plan national<\/a>\u00a0et la reconnaissance de l\u2019endom\u00e9triose comme Affection Longue Dur\u00e9e (ALD). L’endom\u00e9triose entre alors pleinement dans notre histoire et dans notre soci\u00e9t\u00e9.<\/p>

L\u2019histoire de l\u2019endom\u00e9triose est plus que jamais d\u2019actualit\u00e9 alors qu\u2019elle remonte \u00e0 plus de 4000 ans !<\/strong> 190 millions de personnes sont atteintes d’endom\u00e9triose dans le monde, dont 2 millions en France, et pourtant cette maladie semble seulement \u00e9merger depuis une dizaine d\u2019ann\u00e9es. Elle a sans doute souffert d’\u00eatre une maladie \u201cde femmes\u201d, certainement moins consid\u00e9r\u00e9e par les hommes savants au fil des \u00e2ges. Qu\u2019on se le dise ! Loin des d\u00e9lires hyst\u00e9riques et autres \u201cchochotteries\u201d, l\u2019endom\u00e9triose est une r\u00e9elle pathologie qui m\u00e9rite toute l\u2019attention de la m\u00e9decine.<\/b><\/span><\/p>

Comment savoir si j\u2019ai une endom\u00e9triose ?<\/a><\/p>

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\ud83d\udc40 Sources : <\/em>ici<\/em><\/a>,\u00a0ici<\/em><\/a>,\u00a0ici<\/em><\/a>,\u00a0ici<\/em><\/a>,\u00a0ici<\/em><\/a>,\u00a0ici<\/em><\/a>,\u00a0ici<\/em><\/a>,\u00a0ici<\/em><\/a>\u00a0et<\/em>\u00a0l\u00e0<\/em><\/a>\u00a0– Cr\u00e9dits visuels : DR<\/em><\/p>

Disclaimer : je ne suis ni m\u00e9decin, ni historienne. Cet article est le fruit de recherches et du recoupement de diff\u00e9rentes sources accessibles en ligne sur l’histoire de l’endom\u00e9triose.<\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t

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\n\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\tEn savoir plus sur endoyellow.com<\/span>\n\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/a>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t
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L\u2019endom\u00e9triose, on en parle de plus en plus et c\u2019est une tr\u00e8s bonne chose ! Pour autant, on parle peu de QUI a d\u00e9couvert l\u2019endom\u00e9triose. Et surtout QUAND ? \ud83e\uddd0 Et si tu partais \u00e0 la d\u00e9couverte de l\u2019histoire de l\u2019endom\u00e9triose ?<\/p>\n","protected":false},"author":1,"featured_media":1295,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"categories":[22],"tags":[66,26,28,27,85,58,49,40],"class_list":["post-1293","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-se-changer-les-idees","tag-actualite","tag-diagnostic","tag-docteur","tag-douleur","tag-education","tag-sinformer","tag-sante","tag-traitement"],"yoast_head":"\nHistoire de l'endom\u00e9triose - endoyellow<\/title>\n<meta name=\"description\" content=\"On a le sentiment que l'endom\u00e9triose est une maladie nouvelle, mais est-ce vraiment le cas ? 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